Cardiovascular diseases begin in a woman’s reproductive organs, namely cervix, endometrium, fallopian tubes, ovaries, uterus, vagina, and vulva. This segment dominated the market because of the increased prevalence of cardiovascular diseases among people worldwide. According to data provided by WHO, an estimate says that 1.13 billion people suffer from hypertension globally. Many new therapies are being introduced for treating these disorders including a combination of treatments, and many more.
Efficacy of Combination of Drugs:
- In October 2022, South Korea-based Jeil Pharmaceutical announced its four-drug combination therapy called as TelmicanQ for treating hypertension and dyslipidemia. This drug combination TelmicanQ contains four constituents --telmisartan, rosuvastatin calcium, ezetimibe, and amlodipine besylate—in a single tablet.
- In November 2021, the Subject Expert Committee operational under the Central Drugs Standard Control Organization(CDSCO) in India granted Torrent Pharmaceuticals more strength of fixed-dose combination drug Amlodipine Besylate USP eq. to Amlodipine 10mg and Olmesartan Medoxomil USP 40mg Tablet by approving the waiver of the phase 3 clinical trial. In patients with medium-grade to high-grade hypertension, this combination was considerably more effective than individual administration of these drugs in lowering blood pressure and accomplishing standard blood pressure targets.
- In March 2023, a study conducted by All India Institute of Medical Sciences, Bhubaneswar, India compared the efficacy and safety of azilsartan and amlodipine combination versus telmisartan and amlodipine combination in hypertensive patients, where azilsartan amlodipine combination had an 88% response rate, which was superior to the other combination of telmisartan and amlodipine.
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Cure of Anal Fissures:
- In June 2023, US-based clinical-stage specialty pharmaceutical company Tavanta Therapeutics, presented new data from its anal fissure program during the American Society of Colon and Rectal Surgeons (ASCRS) Annual Meeting. They presented the first data from their Phase 2 study of TAVT-119, an amlodipine besylate gel in people suffering from chronic anal fissures. TAVT-119 can be applied topically without significant systemic exposure and is believed to have the capacity to offer patients a treatment option that provides safety as well as efficacy.
Grants & Discounts:
- In September 2023, Connecticut’s Governor Ned Lamont and State Comptroller Sean Scanlon launched a new prescription drug discount program, that will permit all state residents to access discounts on their prescription drugs using a discount card, called Array RX, which is a free digital card. The program confirmed offering discounts at 98% of pharmacies across Connecticut which would help in saving up to 80% on generic drugs and 20% on brand-name drugs. Expectedly, amlodipine besylate 5 mg – 30 tablets which are provided at a cost of USD 50.64 will be provided at USD 8.22 under this program.
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Acceptance and Progression:
These techniques give hope of treating cardiovascular diseases effectively. With the dignified applications, these techniques will hopefully burgeon the global cardiovascular diseases market in upcoming years. However, the journey towards universal adoption of new therapies comes with its challenges. Primary concerns include the safety implications and the high costs associated with these therapies, which may limit their accessibility. The evolution of cardiovascular disease therapeutics using cardiovascular disease therapeutics is undeniably transforming the way we approach cardiovascular disease therapeutics. The current trajectory is anticipated to continue to elevate, bringing hope to patients and shaking up the healthcare market in an unparalleled way.
Conclusion
Despite the hurdles, the future of cardiovascular disease therapeutics is undeniably bright. A new dawn is breaking in the treatment of cardiovascular diseases using amlodipine besylate. The remarkable investment interest, the promising results of ongoing clinical trials, and the scientific community's unwavering commitment are fueling a health revolution. There's no denying it - advanced therapeutics is transforming the way of management of cardiovascular diseases, bringing hope to patients worldwide. According to the UnivDatos Market Insights analysis, the surge in the incidences of unhealthy lifestyle prevalence and the associated surge in the demand for cardiovascular diseases therapeutics will drive the global market of Amlodipine Besylate and as per their “Amlodipine Besylate Market” report, the global market was valued at USD 350 million in 2022, growing at a CAGR of 4.5% during the forecast period from 2023 - 2030 to reach USD 410 million by 2030.
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